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Resveratrol Downregulates Cyp2e1 and Attenuates Chemically Induced Hepatocarcinogenesis in SD Rats

Cyp2e1 plays an important role in chemically induced hepatocarcinogenesis. Resveratrol (REV) is known to prevent diethylnitrosamine (DEN)-induced hepatocarcinogenesis, but its effects on this process induced by DEN and 2-acetylaminofluorene (2-AAF) and the role of Cyp2e1 remain unclear. In this stud...

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Hlavní autoři: Wu, Xiongfei, Li, Chenggang, Xing, Guozhen, Qi, Xinming, Ren, Jin
Médium: Artigo
Jazyk:Inglês
Vydáno: Japanese Society of Toxicologic Pathology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921921/
https://ncbi.nlm.nih.gov/pubmed/24526811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2013-0020
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