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Granzyme M: behind enemy lines
The granule-exocytosis pathway is the major mechanism via which cytotoxic lymphocytes eliminate virus-infected and tumor cells. In this pathway, cytotoxic lymphocytes release granules containing the pore-forming protein perforin and a family of serine proteases known as granzymes into the immunologi...
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Nature Publishing Group
2014
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3921602/ https://ncbi.nlm.nih.gov/pubmed/24413154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.189 |
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