Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes

The guanylyl cyclases, GC-A and GC-B, are selective receptors for atrial and C-type natriuretic peptides (ANP and CNP, respectively). In the anterior pituitary, CNP and GC-B are major regulators of cGMP production in gonadotropes and yet mouse models of disrupted CNP and GC-B indicate a potential ro...

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Autori principali: Thompson, Iain R., Mirczuk, Samantha M., Smith, Lorna, Lessey, Andrew J., Simbi, Bigboy, Sunters, Andrew, Baxter, Gary F., Lipscomb, Victoria J., McGonnell, Imelda M., Wheeler-Jones, Caroline P., Mukherjee, Abir, Roberson, Mark S., McArdle, Craig A., Fowkes, Robert C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2013
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Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921447/
https://ncbi.nlm.nih.gov/pubmed/24352806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-013-1763-y
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