Natriuretic Peptide Expression and Function in GH3 Somatolactotropes and Feline Somatotrope Pituitary Tumours

Patients harbouring mutations in genes encoding C-type natriuretic peptide (CNP; NPPC) or its receptor guanylyl cyclase B (GC-B, NPR2) suffer from severe growth phenotypes; loss-of-function mutations cause achondroplasia, whereas gain-of-function mutations cause skeletal overgrowth. Although most of...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Mirczuk, Samantha M., Scudder, Christopher J., Read, Jordan E., Crossley, Victoria J., Regan, Jacob T., Richardson, Karen M., Simbi, Bigboy, McArdle, Craig A., Church, David B., Fenn, Joseph, Kenny, Patrick J., Volk, Holger A., Wheeler-Jones, Caroline P., Korbonits, Márta, Niessen, Stijn J., McGonnell, Imelda M., Fowkes, Robert C.
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865297/
https://ncbi.nlm.nih.gov/pubmed/33499110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031076
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