Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RAR beta 2 and Hoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts.

By using RAR type (alpha, beta, or gamma)-specific synthetic retinoids and a pan-retinoic X receptor (RXR)-specific ligand, we have investigated the contribution of RARs and RXRs in the activation of RA target genes and the differentiation of embryonal carcinoma cells. We demonstrate cell-type- and...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Taneja, R, Roy, B, Plassat, J L, Zusi, C F, Ostrowski, J, Reczek, P R, Chambon, P
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1996
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC39213/
https://ncbi.nlm.nih.gov/pubmed/8650243
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