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Management of thrombotic thrombocytopenic purpura: current perspectives

Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening thrombotic microangiopathy which causes significant morbidity and mortality unless promptly recognized and treated. The underlying pathogenesis of TTP is a severe deficiency in ADAMTS13 activity, a metalloprotease that cleaves ult...

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Bibliografiske detaljer
Main Authors: Blombery, Piers, Scully, Marie
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921093/
https://ncbi.nlm.nih.gov/pubmed/24523598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JBM.S46458
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