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Single Nucleotide Polymorphisms in MicroRNA Binding Sites of Oncogenes: Implications in Cancer and Pharmacogenomics
Cancer, a complex genetic disease involving uncontrolled cell proliferation, is caused by inactivation of tumor suppressor genes and activation of oncogenes. A vast majority of these cancer causing genes are known targets of microRNAs (miRNAs) that bind to complementary sequences in 3′ untranslated...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Mary Ann Liebert, Inc.
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3920756/ https://ncbi.nlm.nih.gov/pubmed/24286505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/omi.2013.0098 |
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