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Role of Adenosine and the Orexinergic Perifornical Hypothalamus in Sleep-Promoting Effects of Ethanol

STUDY OBJECTIVES: Strong clinical and preclinical evidence suggests that acute ethanol promotes sleep. However, very little is known about how and where ethanol acts to promote sleep. We hypothesized that ethanol may induce sleep by increasing extracellular levels of adenosine and inhibiting orexin...

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Detalhes bibliográficos
Main Authors: Sharma, Rishi, Sahota, Pradeep, Thakkar, Mahesh M.
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920318/
https://ncbi.nlm.nih.gov/pubmed/24587575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.3490
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