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Methylglyoxal (MG) and Cerebro-Renal Interaction: Does Long-Term Orally Administered MG Cause Cognitive Impairment in Normal Sprague-Dawley Rats?

Methylglyoxal (MG), one of the uremic toxins, is a highly reactive alpha-dicarbonyl compound. Recent clinical studies have demonstrated the close associations of cognitive impairment (CI) with plasma MG levels and presence of kidney dysfunction. Therefore, the present study aims to examine whether M...

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Detalhes bibliográficos
Main Authors: Watanabe, Kimio, Okada, Kana, Fukabori, Ryoji, Hayashi, Yoshimitsu, Asahi, Koichi, Terawaki, Hiroyuki, Kobayashi, Kazuto, Watanabe, Tsuyoshi, Nakayama, Masaaki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920260/
https://ncbi.nlm.nih.gov/pubmed/24402234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins6010254
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