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Methylglyoxal (MG) and Cerebro-Renal Interaction: Does Long-Term Orally Administered MG Cause Cognitive Impairment in Normal Sprague-Dawley Rats?

Methylglyoxal (MG), one of the uremic toxins, is a highly reactive alpha-dicarbonyl compound. Recent clinical studies have demonstrated the close associations of cognitive impairment (CI) with plasma MG levels and presence of kidney dysfunction. Therefore, the present study aims to examine whether M...

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Autors principals: Watanabe, Kimio, Okada, Kana, Fukabori, Ryoji, Hayashi, Yoshimitsu, Asahi, Koichi, Terawaki, Hiroyuki, Kobayashi, Kazuto, Watanabe, Tsuyoshi, Nakayama, Masaaki
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920260/
https://ncbi.nlm.nih.gov/pubmed/24402234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins6010254
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