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Dehydroepiandrosterone promotes pulmonary artery relaxation by NADPH oxidation-elicited subunit dimerization of protein kinase G 1α

The activity of glucose-6-phosphate dehydrogenase (G6PD) controls a vascular smooth muscle relaxing mechanism promoted by the oxidation of cytosolic NADPH, which has been associated with activation of the 1α form of protein kinase G (PKG-1α) by a thiol oxidation-elicited subunit dimerization. This P...

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Библиографические подробности
Главные авторы: Patel, Dhara, Kandhi, Sharath, Kelly, Melissa, Neo, Boon Hwa, Wolin, Michael S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920223/
https://ncbi.nlm.nih.gov/pubmed/24375799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00301.2013
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