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Regulation and activity of secretory leukoprotease inhibitor (SLPI) is altered in smokers

A hallmark of cigarette smoking is a shift in the protease/antiprotease balance, in favor of protease activity. However, it has recently been shown that smokers have increased expression of a key antiprotease, secretory leukoprotease inhibitor (SLPI), yet the mechanisms involved in SLPI transcriptio...

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Hlavní autoři: Meyer, Megan, Bauer, Rebecca N., Letang, Blanche D., Brighton, Luisa, Thompson, Elizabeth, Simmen, Rosalia C. M., Bonner, James, Jaspers, Ilona
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920198/
https://ncbi.nlm.nih.gov/pubmed/24285265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00290.2013
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