Increased Susceptibility to LPS-induced Endotoxin Shock in Secretory Leukoprotease Inhibitor (SLPI)-deficient Mice

Secretory leukoprotease inhibitor (SLPI) protects tissue against the destructive action of neutrophil elastase at the site of inflammation. Recent studies on new functions of SLPI have demonstrated that SLPI may play a larger role in innate immunity than merely as a protease inhibitor. To clarify th...

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Autores principales: Nakamura, Akira, Mori, Yuriko, Hagiwara, Koichi, Suzuki, Takuji, Sakakibara, Tomohiro, Kikuchi, Toshiaki, Igarashi, Takayuki, Ebina, Masahito, Abe, Tatsuya, Miyazaki, Junichi, Takai, Toshiyuki, Nukiwa, Toshihiro
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2003
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193830/
https://ncbi.nlm.nih.gov/pubmed/12615907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021824
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