Insulin dysfunction and Tau pathology

The neuropathological hallmarks of Alzheimer's disease (AD) include senile plaques of β-amyloid (Aβ) peptides (a cleavage product of the Amyloid Precursor Protein, or APP) and neurofibrillary tangles (NFT) of hyperphosphorylated Tau protein assembled in paired helical filaments (PHF). NFT patho...

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Autores principales: El Khoury, Noura B., Gratuze, Maud, Papon, Marie-Amélie, Bretteville, Alexis, Planel, Emmanuel
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920186/
https://ncbi.nlm.nih.gov/pubmed/24574966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00022
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