Cardiomyocyte Ogt is essential for postnatal viability

The singly coded gene O-linked-β-N-acetylglucosamine (O-GlcNAc) transferase (Ogt) resides on the X chromosome and is necessary for embryonic stem cell viability during embryogenesis. In mature cells, this enzyme catalyzes the posttranslational modification known as O-GlcNAc to various cellular prote...

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Autors principals: Watson, Lewis J., Long, Bethany W., DeMartino, Angelica M., Brittian, Kenneth R., Readnower, Ryan D., Brainard, Robert E., Cummins, Timothy D., Annamalai, Lakshmanan, Hill, Bradford G., Jones, Steven P.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
Matèries:
Integrative Cardiovascular Physiology and Pathophysiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920156/
https://ncbi.nlm.nih.gov/pubmed/24186210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00438.2013
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