Endothelial actin depolymerization mediates NADPH oxidase-superoxide production during flow reversal

Slow moving blood flow and changes in flow direction, e.g., negative wall shear stress, can cause increased superoxide (O(2)(·−)) production in vascular endothelial cells. The mechanism by which shear stress increases O(2)(·−) production, however, is not well established. We tested the hypothesis th...

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Bibliografiske detaljer
Main Authors: Choy, Jenny S., Lu, Xiao, Yang, Junrong, Zhang, Zhen-Du, Kassab, Ghassan S.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2013
Fag:
Vascular Biology and Microcirculation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920148/
https://ncbi.nlm.nih.gov/pubmed/24186098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00402.2013
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