Nox-derived ROS are acutely activated in pressure overload pulmonary hypertension: indications for a seminal role for mitochondrial Nox4

Pulmonary arterial hypertension is a severe progressive disease with marked morbidity and high mortality in which right ventricular (RV) failure is the major cause of death. Thus knowledge of the mechanisms underlying RV failure is an area of active interest. Previous studies suggest a role of NADPH...

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Autori principali: Frazziano, Giovanna, Al Ghouleh, Imad, Baust, Jeff, Shiva, Sruti, Champion, Hunter C., Pagano, Patrick J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2013
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Call for Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920131/
https://ncbi.nlm.nih.gov/pubmed/24213612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00977.2012
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