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Functional consequences of EpCam mutation in mice and men

Congenital tufting enteropathy (CTE) is a severe diarrheal disease of infancy characterized by villous changes and epithelial tufts. We previously identified mutations in epithelial cell adhesion molecule (EpCAM) as the cause of CTE. We developed an in vivo mouse model of CTE based on EpCAM mutation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mueller, James L., McGeough, Matthew D., Peña, Carla A., Sivagnanam, Mamata
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920125/
https://ncbi.nlm.nih.gov/pubmed/24337010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00286.2013
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