Precision-cut liver slices from diet-induced obese rats exposed to ethanol are susceptible to oxidative stress and increased fatty acid synthesis

Oxidative stress from fat accumulation in the liver has many deleterious effects. Many believe that there is a second hit that causes relatively benign fat accumulation to transform into liver failure. Therefore, we evaluated the effects of ethanol on ex vivo precision-cut liver slice cultures (PCLS...

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Detalhes bibliográficos
Main Authors: Duryee, Michael J., Willis, Monte S., Schaffert, Courtney S., Reidelberger, Roger D., Dusad, Anand, Anderson, Daniel R., Klassen, Lynell W., Thiele, Geoffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Liver and Biliary Tract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920111/
https://ncbi.nlm.nih.gov/pubmed/24284960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00124.2013
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