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Autoimmune Hepatitis Induced by Syngeneic Liver Cytosolic Proteins Biotransformed by Alcohol Metabolites

BACKGROUND & AIMS: Aldehydes that are produced following the breakdown of ethanol (acetaldehyde) and lipid peroxidation of membranes (malondialdehyde) have been shown to bind (adduct) proteins. Additionally, these two aldehydes can combine (MAA) on non-syngeneic and syngeneic proteins to initiat...

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Hlavní autoři: Thiele, Geoffrey M., Duryee, Michael J., Willis, Monte S., Tuma, Dean J., Radio, Stanley J., Hunter, Carlos D., Schaffert, Courtney S., Klassen, Lynell W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014581/
https://ncbi.nlm.nih.gov/pubmed/20860619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2010.01309.x
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