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A dual role for the Ca2+-requiring proteinase in the degradation of hemoglobin by erythrocyte membrane proteinases.

Binding of hemoglobin chains to erythrocyte membranes is an obligatory step in the conversion of hemoglobin to acid-soluble products by erythrocyte proteinases. This binding requires limited proteolysis of the hemoglobin chains and also modification of the inner surface of the erythrocyte membrane,...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Pontremoli, S, Melloni, E, Sparatore, B, Michetti, M, Horecker, B L
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1984
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392001/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6093116/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.21.6714
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