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An endogenous activator of the Ca2+-dependent proteinase of human neutrophils that increases its affinity for Ca2+.

An endogenous activator of the Ca2+-dependent proteinase (calpain) has been identified in human neutrophils. In the presence of the activator, the affinity of calpain for Ca2+ is increased by greater than 100-fold and maximum catalytic activity is observed with Ca2+ concentration below 1 microM. The...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Pontremoli, S, Melloni, E, Michetti, M, Salamino, F, Sparatore, B, Horecker, B L
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279854/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2831536/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.6.1740
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