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Prostaglandin E2 induces chloride secretion through crosstalk between cAMP and calcium signaling in mouse inner medullary collecting duct cells

Under conditions of high dietary salt intake, prostaglandin E2 (PGE2) production is increased in the collecting duct and promotes urinary sodium chloride (NaCl) excretion; however, the molecular mechanisms by which PGE2 increases NaCl excretion in this context have not been clearly defined. We used...

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Autori principali: Rajagopal, Madhumitha, Thomas, Sheela V., Kathpalia, Paru P., Chen, Yu, Pao, Alan C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920002/
https://ncbi.nlm.nih.gov/pubmed/24284792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00381.2012
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