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Activation of P2Y(1) and P2Y(2) receptors induces chloride secretion via calcium-activated chloride channels in kidney inner medullary collecting duct cells

Dysregulation of urinary sodium chloride (NaCl) excretion can result in extracellular fluid (ECF) volume expansion and hypertension. Recent studies demonstrated that urinary nucleotide excretion increases in mice ingesting a high-salt diet and that these increases in extracellular nucleotides can si...

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Библиографические подробности
Главные авторы: Rajagopal, Madhumitha, Kathpalia, Paru P., Thomas, Sheela V., Pao, Alan C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174549/
https://ncbi.nlm.nih.gov/pubmed/21653634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00709.2010
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