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Permeability dependence study of the focused ultrasound-induced blood-brain barrier opening at distinct pressures and microbubble diameters using DCE-MRI

Blood-brain barrier (BBB) opening using focused ultrasound (FUS) and microbubbles has been experimentally established as a non-invasive and localized brain drug delivery technique. In this study, the permeability of the opening is assessed in the murine hippocampus after the application of FUS at th...

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Bibliographic Details
Main Authors: Vlachos, Fotios, Tung, Yao-Sheng, Konofagou, Elisa
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919956/
https://ncbi.nlm.nih.gov/pubmed/21465543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.22848
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