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Sodium 4-phenylbutyrate suppresses the development of dextran sulfate sodium-induced colitis in mice

Sodium 4-phenylbutyrate (PBA) exhibits anti-inflammatory effects by suppressing nuclear factor-κB (NF-κB) activation. In the present study, the effects of PBA on a mouse model of dextran sulfate sodium (DSS)-induced colitis were investigated. The therapeutic efficacy of PBA (150 mg/kg body weight) i...

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Autors principals: ONO, KAZUHIKO, NIMURA, SATOSHI, NISHINAKAGAWA, TAKUYA, HIDESHIMA, YUKO, ENJYOJI, MUNECHIKA, NABESHIMA, KAZUKI, NAKASHIMA, MANABU
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919895/
https://ncbi.nlm.nih.gov/pubmed/24520247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2013.1456
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