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Ultrastructure of microglia-synapse interactions in the HIV-1 Tat-injected murine central nervous system

The destruction of normal synaptic architecture is the main pathogenetic substrate in HIV-associated neurocognitive disorder (HAND), but the sequence of cellular events underlying this outcome is not completely understood. Our recent work in a mouse model of HAND using a single intraparenchymal inje...

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Autores principales: Tremblay, Marie-Ève, Marker, Daniel F, Puccini, Jenna M, Muly, E Chris, Lu, Shao-Ming, Gelbard, Harris A
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919816/
https://ncbi.nlm.nih.gov/pubmed/24563721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.27670
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