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Wild-type K-ras has a tumour suppressor effect on carcinogen-induced murine colorectal adenoma formation
K-ras mutations are found in ∼40% of human colorectal adenomas and carcinomas and contribute to colorectal tumour formation at an early stage. Wild-type K-ras has been reported to be deleted in some tumours, but the consequences of changes in wild-type K-ras copy number for experimental colorectal c...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3919644/ https://ncbi.nlm.nih.gov/pubmed/24354449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12064 |
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