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Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7.

We have shown previously that an increase in the level of accumulated pS2 mRNA is first detectable in MCF-7 cells after 3 hr of estradiol treatment. Using in vitro nuclear run-on transcription with nuclei prepared from MCF-7 cells grown in the presence of estradiol or in estradiol-stripped medium, w...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Brown, A M, Jeltsch, J M, Roberts, M, Chambon, P
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1984
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391920/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6593703/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.20.6344
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