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Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7.

We have shown previously that an increase in the level of accumulated pS2 mRNA is first detectable in MCF-7 cells after 3 hr of estradiol treatment. Using in vitro nuclear run-on transcription with nuclei prepared from MCF-7 cells grown in the presence of estradiol or in estradiol-stripped medium, w...

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Библиографические подробности
Главные авторы: Brown, A M, Jeltsch, J M, Roberts, M, Chambon, P
Формат: Artigo
Язык:Inglês
Опубликовано: 1984
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC391920/
https://ncbi.nlm.nih.gov/pubmed/6593703
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