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DNA methylation profiling in X;autosome translocations supports a role for L1 repeats in the spread of X chromosome inactivation

X chromosome inactivation (XCI) is an epigenetic mechanism that silences the majority of genes on one X chromosome in females. Previous studies have suggested that the spread of XCI might be facilitated in part by common repeats such as long interspersed nuclear elements (LINEs). However, owing to t...

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Autori principali: Bala Tannan, Neeta, Brahmachary, Manisha, Garg, Paras, Borel, Christelle, Alnefaie, Randah, Watson, Corey T., Thomas, N. Simon, Sharp, Andrew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919006/
https://ncbi.nlm.nih.gov/pubmed/24186870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt553
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