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DNA methylation profiling in X;autosome translocations supports a role for L1 repeats in the spread of X chromosome inactivation

X chromosome inactivation (XCI) is an epigenetic mechanism that silences the majority of genes on one X chromosome in females. Previous studies have suggested that the spread of XCI might be facilitated in part by common repeats such as long interspersed nuclear elements (LINEs). However, owing to t...

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書誌詳細
主要な著者: Bala Tannan, Neeta, Brahmachary, Manisha, Garg, Paras, Borel, Christelle, Alnefaie, Randah, Watson, Corey T., Thomas, N. Simon, Sharp, Andrew J.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919006/
https://ncbi.nlm.nih.gov/pubmed/24186870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt553
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