Rationale and study design of the Prospective comparison of Angiotensin Receptor neprilysin inhibitor with Angiotensin receptor blocker MEasuring arterial sTiffness in the eldERly (PARAMETER) study

INTRODUCTION: Hypertension in elderly people is characterised by elevated systolic blood pressure (SBP) and increased pulse pressure (PP), which indicate large artery ageing and stiffness. LCZ696, a first-in-class angiotensin receptor neprilysin inhibitor (ARNI), is being developed to treat hyperten...

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Detalhes bibliográficos
Main Authors: Williams, Bryan, Cockcroft, John R, Kario, Kazuomi, Zappe, Dion H, Cardenas, Pamela, Hester, Allen, Brunel, Patrick, Zhang, Jack
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Cardiovascular Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918996/
https://ncbi.nlm.nih.gov/pubmed/24496699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2013-004254
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