CD19 and CD32b Differentially Regulate Human B Cell Responsiveness

B cell activation is regulated by a variety of signals. CD19 positively regulates B cell activation, augmenting signals delivered through the BCR complex. In contrast, CD32b contains an ITIM and negatively regulates BCR signaling. Importantly, there are drugs currently in clinical trials and preclin...

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Bibliografische gegevens
Hoofdauteurs: Karnell, Jodi L., Dimasi, Nazzareno, Karnell, Fredrick G., Fleming, Ryan, Kuta, Ellen, Wilson, Mildred, Wu, Herren, Gao, Changshou, Herbst, Ronald, Ettinger, Rachel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: AAI 2014
Onderwerpen:
Clinical and Human Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918864/
https://ncbi.nlm.nih.gov/pubmed/24442430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301361
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