CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing

Repressive histone H3 lysine 9 methylation (H3K9me) and its recognition by HP1 proteins are necessary for pericentromeric heterochromatin formation. In Schizosaccharomyces pombe, H3K9me deposition depends on the RNAi pathway. Cryptic loci regulator 4 (Clr4), the only known H3K9 methyltransferase in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kuscu, Canan, Zaratiegui, Mikel, Kim, Hyun Soo, Wah, David A., Martienssen, Robert A., Schalch, Thomas, Joshua-Tor, Leemor
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2014
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918804/
https://ncbi.nlm.nih.gov/pubmed/24449894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313096111
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