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Metformin Inhibits Skin Tumor Promotion in Overweight and Obese Mice

In the present study, the ability of metformin to inhibit skin tumor promotion by 12-O- tetradecanoylphorbol-13-acetate (TPA) was analyzed in mice maintained on either an overweight control diet or an obesity inducing diet. Rapamycin was included for comparison, and a combination of metformin and ra...

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Main Authors: Checkley, L. Allyson, Rho, Okkyung, Angel, Joe M., Cho, Jiyoon, Blando, Jorge, Beltran, Linda, Hursting, Stephen D., DiGiovanni, John
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918668/
https://ncbi.nlm.nih.gov/pubmed/24196830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0110
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