Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

Alternative splicing (AS) enables programmed diversity of gene expression across tissues and development. We show here that binding in distal intronic regions (>500 nucleotides (nt) from any exon) by Rbfox splicing factors important in development is extensive and is an active mode of splicing re...

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Detalhes bibliográficos
Main Authors: Lovci, Michael T, Ghanem, Dana, Marr, Henry, Arnold, Justin, Gee, Sherry, Parra, Marilyn, Liang, Tiffany Y, Stark, Thomas J, Gehman, Lauren T, Hoon, Shawn, Massirer, Katlin B, Pratt, Gabriel A, Black, Douglas L, Gray, Joe W, Conboy, John G, Yeo, Gene W
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918504/
https://ncbi.nlm.nih.gov/pubmed/24213538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2699
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