Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO, and CCFR Consortia

OBJECTIVE: Genome-wide association studies (GWAS) have identified a large number of single nucleotide polymorphisms (SNPs) associated with a wide array of cancer sites. Several of these variants demonstrate associations with multiple cancers, suggesting pleiotropic effects and shared biological mech...

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主要な著者: Cheng, Iona, Kocarnik, Jonathan M, Dumitrescu, Logan, Lindor, Noralane M, Chang-Claude, Jenny, Avery, Christy L., Caberto, Christian P, Love, Shelly-Ann, Slattery, Martha L, Chan, Andrew T, Baron, John A, Hindorff, Lucia A, Park, Sungshim Lani, Schumacher, Fredrick R, Hoffmeister, Michael, Kraft, Peter, Butler, Anne, Duggan, David, Hou, Lifang, Carlson, Chris S, Monroe, Kristine R, Lin, Yi, Carty, Cara L, Mann, Sue, Ma, Jing, Giovannucci, Edward L, Fuchs, Charles S, Newcomb, Polly A, Jenkins, Mark A, Hopper, John L, Haile, Robert W, Conti, David V, Campbell, Peter T, Potter, John D, Caan, Bette J, Schoen, Robert E, Hayes, Richard B, Chanock, Stephen J, Berndt, Sonja I, Kury, Sebastien, Bezieau, Stephane, Ambite, Jose Luis, Kumaraguruparan, Gowri, Richardson, Danielle, Goodloe, Robert J, Dilks, Holli H, Baker, Paxton, Zanke, Brent W, Lemire, Mathieu, Gallinger, Steven, Hsu, Li, Jiao, Shuo, Harrison, Tabitha, Seminara, Daniela, Haiman, Christopher A, Kooperberg, Charles, Wilkens, Lynne R, Hutter, Carolyn M, White, Emily, Crawford, Dana C, Heiss, Gerardo, Hudson, Thomas J, Brenner, Hermann, Bush, William S, Casey, Graham, Marchand, Loic Le, Peters, Ulrike
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918490/
https://ncbi.nlm.nih.gov/pubmed/23935004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-305189
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