Nanobodies targeting mouse/human VCAM1 for the nuclear imaging of atherosclerotic lesions

RATIONALE: There is a well-recognized need for a noninvasive tool allowing the detection of vulnerable atherosclerotic plaques. By combining nanomolar affinities and fast blood clearance, nanobodies represent potential generic radiotracers for cardiovascular molecular imaging. As an inflammatory mar...

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Hauptverfasser: Broisat, Alexis, Hernot, Sophie, Toczek, Jakub, De Vos, Jens, Riou, Laurent M., Martin, Sandrine, Ahmadi, Mitra, Thielens, Nicole, Wernery, Ulrich, Caveliers, Vicky, Muyldermans, Serge, Lahoutte, Tony, Fagret, Daniel, Ghezzi, Catherine, Devoogdt, Nick
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918224/
https://ncbi.nlm.nih.gov/pubmed/22461363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.265140
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