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Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity.

The S107 IgA kappa-chain myeloma cell line makes an antiphosphocholine antibody of the T15 idiotype. A somatic mutant of this line, U4, makes an immunoglobulin with a single amino acid substitution of an alanine for a glutamic acid at residue 35. This single amino acid change results in a loss of ph...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Diamond, B, Scharff, M D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1984
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC391807/
https://ncbi.nlm.nih.gov/pubmed/6435121
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