Multiple gene deletions within the human immunoglobulin heavy-chain cluster.
Two subjects, of 11,000 healthy individuals screened, were found to be missing three and four immunoglobulin isotypes, respectively (IgA1, IgG2, and IgG4; IgA1, IgG2, IgG4, and IgE), and have been analyzed at the DNA level by means of Southern blotting and Ig heavy-chain-specific probes. A broad del...
Guardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1984
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391801/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6435120/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.18.5811 |
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