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Multiple gene deletions within the human immunoglobulin heavy-chain cluster.

Two subjects, of 11,000 healthy individuals screened, were found to be missing three and four immunoglobulin isotypes, respectively (IgA1, IgG2, and IgG4; IgA1, IgG2, IgG4, and IgE), and have been analyzed at the DNA level by means of Southern blotting and Ig heavy-chain-specific probes. A broad del...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Migone, N, Oliviero, S, de Lange, G, Delacroix, D L, Boschis, D, Altruda, F, Silengo, L, DeMarchi, M, Carbonara, A O
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1984
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391801/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6435120/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.18.5811
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