TLR2, TLR4 and CD14 Recognize Venom-Associated Molecular Patterns from Tityus serrulatus to Induce Macrophage-Derived Inflammatory Mediators

Scorpion sting-induced human envenomation provokes an intense inflammatory reaction. However, the mechanisms behind the recognition of scorpion venom and the induction of mediator release in mammalian cells are unknown. We demonstrated that TLR2, TLR4 and CD14 receptors sense Tityus serrulatus venom...

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Bibliografiset tiedot
Päätekijät: Zoccal, Karina Furlani, Bitencourt, Claudia da Silva, Paula-Silva, Francisco Wanderley Garcia, Sorgi, Carlos Artério, de Castro Figueiredo Bordon, Karla, Arantes, Eliane Candiani, Faccioli, Lúcia Helena
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917877/
https://ncbi.nlm.nih.gov/pubmed/24516606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088174
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