TLR2, TLR4 and CD14 Recognize Venom-Associated Molecular Patterns from Tityus serrulatus to Induce Macrophage-Derived Inflammatory Mediators

Scorpion sting-induced human envenomation provokes an intense inflammatory reaction. However, the mechanisms behind the recognition of scorpion venom and the induction of mediator release in mammalian cells are unknown. We demonstrated that TLR2, TLR4 and CD14 receptors sense Tityus serrulatus venom...

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Detalhes bibliográficos
Main Authors: Zoccal, Karina Furlani, Bitencourt, Claudia da Silva, Paula-Silva, Francisco Wanderley Garcia, Sorgi, Carlos Artério, de Castro Figueiredo Bordon, Karla, Arantes, Eliane Candiani, Faccioli, Lúcia Helena
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917877/
https://ncbi.nlm.nih.gov/pubmed/24516606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088174
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