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Dabrafenib for treatment of BRAF-mutant melanoma

Melanoma has the highest mortality of all the skin cancer subtypes. Historically, chemotherapy and immunologic therapies have yielded only modest results in the treatment of metastatic melanoma. The discovery of prevalent V600 BRAF mutations driving proliferation makes this oncogenic protein an idea...

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Bibliografiske detaljer
Main Authors: Kainthla, Radhika, Kim, Kevin B, Falchook, Gerald S
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917541/
https://ncbi.nlm.nih.gov/pubmed/24516336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S37220
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