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Brd4-Mediated Nuclear Retention of the Papillomavirus E2 Protein Contributes to Its Stabilization in Host Cells

Papillomavirus E2 is a multifunctional viral protein that regulates many aspects of the viral life cycle including viral episome maintenance, transcriptional activation, and repression. E2 is degraded by the ubiquitin-proteasome pathway. Cellular bromodomain protein Brd4 has been implicated in the s...

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Hlavní autoři: Li, Jing, Li, Qing, Diaz, Jason, You, Jianxin
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917445/
https://ncbi.nlm.nih.gov/pubmed/24448221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v6010319
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