Solomonsterol A, a Marine Pregnane-X-Receptor Agonist, Attenuates Inflammation and Immune Dysfunction in a Mouse Model of Arthritis

In the present study we provide evidence that solomonsterol A, a selective pregnane X receptor (PXR) agonist isolated from the marine sponge Theonella swinhoei, exerts anti-inflammatory activity and attenuates systemic inflammation and immune dysfunction in a mouse model of rheumatoid arthritis. Sol...

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Main Authors: Mencarelli, Andrea, D’Amore, Claudio, Renga, Barbara, Cipriani, Sabrina, Carino, Adriana, Sepe, Valentina, Perissutti, Elisa, D’Auria, Maria Valeria, Zampella, Angela, Distrutti, Eleonora, Fiorucci, Stefano
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917259/
https://ncbi.nlm.nih.gov/pubmed/24368568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md12010036
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