Mutation of POL B Causes Lupus in Mice

A replication study of a previous genome-wide association study (GWAS) suggested that a single nucleotide polymorphism (SNP) linked to the POLB gene is associated with systemic lupus erythematosus (SLE). This SNP is correlated with decreased POLB expression (Pol β). To determine if decreased Pol β a...

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Hlavní autoři: Senejani, Alireza G., Liu, Yanfeng, Kidane, Dawit, Maher, Stephen E., Zeiss, Caroline J, Park, Hong-Jae, Kashgarian, Michael, McNiff, Jennifer M., Zelterman, Daniel, Bothwell, Alfred L. M., Sweasy, Joann B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916967/
https://ncbi.nlm.nih.gov/pubmed/24388753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.12.017
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