Mutation of POL B Causes Lupus in Mice

A replication study of a previous genome-wide association study (GWAS) suggested that a single nucleotide polymorphism (SNP) linked to the POLB gene is associated with systemic lupus erythematosus (SLE). This SNP is correlated with decreased POLB expression (Pol β). To determine if decreased Pol β a...

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Hauptverfasser: Senejani, Alireza G., Liu, Yanfeng, Kidane, Dawit, Maher, Stephen E., Zeiss, Caroline J, Park, Hong-Jae, Kashgarian, Michael, McNiff, Jennifer M., Zelterman, Daniel, Bothwell, Alfred L. M., Sweasy, Joann B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916967/
https://ncbi.nlm.nih.gov/pubmed/24388753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.12.017
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