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Rhesus macaque rectal and duodenal tissues exhibit B-cell sub-populations distinct from peripheral blood that continuously secrete antigen-specific IgA in short-term explant cultures

It is becoming increasingly obvious that evaluation of a vaccine aimed at preventing HIV infection should include assessment of induced immunity at mucosal sites of viral entry. Among the most salient immune responses are viral-specific antibodies. A recent report on IgA-secreting plasma cells in hu...

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Bibliografski detalji
Glavni autori: Thomas, Michael A., Demberg, Thorsten, Vargas-Inchaustegui, Diego A., Xiao, Peng, Tuero, Iskra, Venzon, David, Weiss, Deborah, Treece, James, Robert-Guroff, Marjorie
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916903/
https://ncbi.nlm.nih.gov/pubmed/24374153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.12.014
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